The combination of various Chinese herbs with proven antiherpes simplex virus type 1 (HSV-1) action combined with acyclovir has been found to have a stronger anti-HSV-1 action than either the herbs or acyclovir alone. They reduced virus yields in the brain and skin more strongly than acyclovir alone, and exhibited stronger anti-HSV-1 activity in the brain than in the skin, in contrast to acyclovir treatment by itself.

Antiviral Research.  1995 ;27(1-2):19-37).